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Polyglutamylation of tubulin's C-terminal tail controls pausing and motility of kinesin-3 family member KIF1A
The kinesin-3 family member KIF1A plays a critical role in site-specific neuronal cargo delivery during axonal transport. KIF1A cargo is mislocalized in many neurodegenerative diseases, indicating that KIF1A's highly efficient, superprocessive motility along axonal microtubules needs to be tigh...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484136/ https://ncbi.nlm.nih.gov/pubmed/30770469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005765 |
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