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Kinesin-4 KIF21B is a potent microtubule pausing factor
Microtubules are dynamic polymers that in cells can grow, shrink or pause, but the factors that promote pausing are poorly understood. Here, we show that the mammalian kinesin-4 KIF21B is a processive motor that can accumulate at microtubule plus ends and induce pausing. A few KIF21B molecules are s...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383399/ https://ncbi.nlm.nih.gov/pubmed/28290984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24746 |
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