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Kinesin-4 KIF21B is a potent microtubule pausing factor

Microtubules are dynamic polymers that in cells can grow, shrink or pause, but the factors that promote pausing are poorly understood. Here, we show that the mammalian kinesin-4 KIF21B is a processive motor that can accumulate at microtubule plus ends and induce pausing. A few KIF21B molecules are s...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: van Riel, Wilhelmina E, Rai, Ankit, Bianchi, Sarah, Katrukha, Eugene A, Liu, Qingyang, Heck, Albert JR, Hoogenraad, Casper C, Steinmetz, Michel O, Kapitein, Lukas C, Akhmanova, Anna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383399/
https://ncbi.nlm.nih.gov/pubmed/28290984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24746
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