Kinesin-4 KIF21B is a potent microtubule pausing factor

Microtubules are dynamic polymers that in cells can grow, shrink or pause, but the factors that promote pausing are poorly understood. Here, we show that the mammalian kinesin-4 KIF21B is a processive motor that can accumulate at microtubule plus ends and induce pausing. A few KIF21B molecules are s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: van Riel, Wilhelmina E, Rai, Ankit, Bianchi, Sarah, Katrukha, Eugene A, Liu, Qingyang, Heck, Albert JR, Hoogenraad, Casper C, Steinmetz, Michel O, Kapitein, Lukas C, Akhmanova, Anna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Biophysics and Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383399/
https://ncbi.nlm.nih.gov/pubmed/28290984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24746
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