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Interplay between the kinesin and tubulin mechanochemical cycles underlies microtubule tip tracking by the non-motile ciliary kinesin Kif7
Correct localization of Hedgehog effectors to the tip of primary cilia is critical for proper signal transduction. The conserved non-motile kinesin Kif7 defines a “cilium-tip compartment” by localizing to the distal ends of axonemal microtubules. How Kif7 recognizes microtubule ends remains unknown....
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6550315/ https://ncbi.nlm.nih.gov/pubmed/31031197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.04.001 |
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