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Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined the effectiveness of treatment of collagen-induced arthritis (CIA) with a neutralizing mAb to GM-CSF. D...

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Détails bibliographiques
Publié dans:Arthritis Res
Auteurs principaux: Cook, Andrew D, Braine, Emma L, Campbell, Ian K, Rich, Melissa J, Hamilton, John A
Format: Artigo
Langue:Inglês
Publié: BMC 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64841/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11549370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar318
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