Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined the effectiveness of treatment of collagen-induced arthritis (CIA) with a neutralizing mAb to GM-CSF. D...

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Autors principals: Cook, Andrew D, Braine, Emma L, Campbell, Ian K, Rich, Melissa J, Hamilton, John A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC64841/
https://ncbi.nlm.nih.gov/pubmed/11549370
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