Site-1 protease–derived soluble (pro)renin receptor targets vasopressin receptor 2 to enhance urine concentrating capability

The antidiuretic hormone vasopressin (AVP), acting through its type 2 receptor (V(2)R) in the collecting duct (CD), critically controls urine concentrating capability. Here, we report that site-1 protease–derived (S1P-derived) soluble (pro)renin receptor (sPRR) participates in regulation of fluid ho...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Wang, Fei, Xu, Chuanming, Luo, Renfei, Peng, Kexin, Ramkumar, Nirupama, Xie, Shiying, Lu, Xiaohan, Zhao, Long, Zuo, Chang-Jiang, Kohan, Donald E., Yang, Tianxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483716/
https://ncbi.nlm.nih.gov/pubmed/30944256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124174
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