Soluble (pro)renin receptor regulation of ENaC involved in aldosterone signaling in cultured collecting duct cells

We have previously shown that activation of (pro)renin receptor (PRR) induces epithelial Na(+) channel (ENaC) activity in cultured collecting duct cells. Here, we examined the role of soluble PRR (sPRR), the cleavage product of PRR in ENaC regulation, and further tested its relevance to aldosterone...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Wang, Fei, Luo, Renfei, Peng, Kexin, Liu, Xiyang, Xu, Chuanming, Lu, Xiaohan, Soodvilai, Sunhapas, Yang, Tianxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099505/
https://ncbi.nlm.nih.gov/pubmed/31841392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00436.2019
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