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(Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells

Proteinuria is a characteristic of chronic kidney disease and also a causative factor that promotes the disease progression, in part, via activation of the intrarenal renin-angiotensin system (RAS). (Pro)renin receptor (PRR), a newly discovered component of the RAS, binds renin and (pro)renin to pro...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Cell Physiol
Huvudupphovsmän: Fang, Hui, Xu, Chuanming, Lu, Aihua, Zou, Chang-Jiang, Xie, Shiying, Chen, Yanting, Zhou, Li, Liu, Mi, Wang, Lei, Wang, Weidong, Yang, Tianxin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814590/
https://ncbi.nlm.nih.gov/pubmed/28903918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00006.2017
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