Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) s...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Yanxiang, Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, Erik, Andersson, Magnus, Calloe, Kirstine, Egea, Pascal F., Klaerke, Dan Arne, Pusch, Michael, Pedersen, Per Amstrup, Zhou, Z. Hong, Gourdon, Pontus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483157/
https://ncbi.nlm.nih.gov/pubmed/31022181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000218
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