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Structure of the human ClC-1 chloride channel
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) s...
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| Udgivet i: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483157/ https://ncbi.nlm.nih.gov/pubmed/31022181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000218 |
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