Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) s...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Yanxiang, Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, Erik, Andersson, Magnus, Calloe, Kirstine, Egea, Pascal F., Klaerke, Dan Arne, Pusch, Michael, Pedersen, Per Amstrup, Zhou, Z. Hong, Gourdon, Pontus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483157/
https://ncbi.nlm.nih.gov/pubmed/31022181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000218
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