Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) s...

詳細記述

保存先:
書誌詳細
出版年:PLoS Biol
主要な著者: Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Yanxiang, Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, Erik, Andersson, Magnus, Calloe, Kirstine, Egea, Pascal F., Klaerke, Dan Arne, Pusch, Michael, Pedersen, Per Amstrup, Zhou, Z. Hong, Gourdon, Pontus
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483157/
https://ncbi.nlm.nih.gov/pubmed/31022181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000218
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