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Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments
ClC-4 is an intracellular Cl(−)/H(+) exchanger that is highly expressed in the brain and whose dysfunction has been linked to intellectual disability and epilepsy. Here we studied the subcellular localization of human ClC-4 in heterologous expression systems. ClC-4 is retained in the endoplasmic ret...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704486/ https://ncbi.nlm.nih.gov/pubmed/28972156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801951 |
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