TRPA1 channel contributes to myocardial ischemia-reperfusion injury

Myocardial ischemia-reperfusion (I/R) results in the generation of free radicals, accumulation of lipid peroxidation-derived unsaturated aldehydes, variable angina (pain), and infarction. The transient receptor potential ankyrin 1 (TRPA1) mediates pain signaling and is activated by unsaturated aldeh...

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Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Conklin, Daniel J., Guo, Yiru, Nystoriak, Matthew A., Jagatheesan, Ganapathy, Obal, Detlef, Kilfoil, Peter J., Hoetker, Joseph David, Guo, Luping, Bolli, Roberto, Bhatnagar, Aruni
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483018/
https://ncbi.nlm.nih.gov/pubmed/30735434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00106.2018
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