Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease

Studies show maternal obesity is a risk factor for metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) in offspring. Here we evaluated potential mechanisms underlying these phenotypes. Female C57Bl6 mice were fed chow or an obesogenic high-fat/high-sucrose (HF/HS) diet with subsequent ma...

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發表在:Am J Physiol Endocrinol Metab
Main Authors: Thompson, Michael D., Derse, Alaina, Ferey, Jeremie LA, Reid, Michaela, Xie, Yan, Christ, Miranda, Chatterjee, Deyali, Nguyen, Chau, Harasymowicz, Natalia, Guilak, Farshid, Moley, Kelle H., Davidson, Nicholas Oliver
格式: Artigo
語言:Inglês
出版: American Physiological Society 2019
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482665/
https://ncbi.nlm.nih.gov/pubmed/30860882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00474.2018
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