Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease

Studies show maternal obesity is a risk factor for metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) in offspring. Here we evaluated potential mechanisms underlying these phenotypes. Female C57Bl6 mice were fed chow or an obesogenic high-fat/high-sucrose (HF/HS) diet with subsequent ma...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Thompson, Michael D., Derse, Alaina, Ferey, Jeremie LA, Reid, Michaela, Xie, Yan, Christ, Miranda, Chatterjee, Deyali, Nguyen, Chau, Harasymowicz, Natalia, Guilak, Farshid, Moley, Kelle H., Davidson, Nicholas Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482665/
https://ncbi.nlm.nih.gov/pubmed/30860882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00474.2018
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