Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Antibodies are the primary correlate of protection for most licensed vaccines; however, their mechanisms of protection may vary, ranging from physical blockade to clearance via the recruitment of innate immunity. Here, we uncover striking functional diversity in vaccine-induced antibodies driven by...

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Bibliographic Details
Published in:Nat Med
Main Authors: Ackerman, Margaret E., Das, Jishnu, Pittala, Srivamshi, Broge, Thomas, Linde, Caitlyn, Suscovich, Todd J., Brown, Eric P., Bradley, Todd, Natarajan, Harini, Lin, Shu, Sassic, Jessica K., O’Keefe, Sean, Mehta, Nickita, Goodman, Derrick, Sips, Magdalena, Weiner, Joshua A., Tomaras, Georgia D., Haynes, Barton F., Lauffenburger, Douglas A., Bailey-Kellogg, Chris, Roederer, Mario, Alter, Galit
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482471/
https://ncbi.nlm.nih.gov/pubmed/30177821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0161-0
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