Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Antibodies are the primary correlate of protection for most licensed vaccines; however, their mechanisms of protection may vary, ranging from physical blockade to clearance via the recruitment of innate immunity. Here, we uncover striking functional diversity in vaccine-induced antibodies driven by...

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Publicat a:Nat Med
Autors principals: Ackerman, Margaret E., Das, Jishnu, Pittala, Srivamshi, Broge, Thomas, Linde, Caitlyn, Suscovich, Todd J., Brown, Eric P., Bradley, Todd, Natarajan, Harini, Lin, Shu, Sassic, Jessica K., O’Keefe, Sean, Mehta, Nickita, Goodman, Derrick, Sips, Magdalena, Weiner, Joshua A., Tomaras, Georgia D., Haynes, Barton F., Lauffenburger, Douglas A., Bailey-Kellogg, Chris, Roederer, Mario, Alter, Galit
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482471/
https://ncbi.nlm.nih.gov/pubmed/30177821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0161-0
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