Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Antibodies are the primary correlate of protection for most licensed vaccines; however, their mechanisms of protection may vary, ranging from physical blockade to clearance via the recruitment of innate immunity. Here, we uncover striking functional diversity in vaccine-induced antibodies driven by...

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書誌詳細
出版年:Nat Med
主要な著者: Ackerman, Margaret E., Das, Jishnu, Pittala, Srivamshi, Broge, Thomas, Linde, Caitlyn, Suscovich, Todd J., Brown, Eric P., Bradley, Todd, Natarajan, Harini, Lin, Shu, Sassic, Jessica K., O’Keefe, Sean, Mehta, Nickita, Goodman, Derrick, Sips, Magdalena, Weiner, Joshua A., Tomaras, Georgia D., Haynes, Barton F., Lauffenburger, Douglas A., Bailey-Kellogg, Chris, Roederer, Mario, Alter, Galit
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482471/
https://ncbi.nlm.nih.gov/pubmed/30177821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0161-0
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