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The ribosome cooperates with a chaperone to guide multi-domain protein folding
Multi-domain proteins, containing several structural units within a single polypeptide, constitute a large fraction of all proteomes. Co-translational folding is assumed to simplify the conformational search problem for large proteins, but the events leading to correctly folded, functional structure...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6481645/ https://ncbi.nlm.nih.gov/pubmed/30852061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.043 |
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