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Co-translational folding of nascent polypeptides: Multi-layered mechanisms for the efficient biogenesis of functional proteins

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co-translational folding and disti...

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Bibliografische gegevens
Gepubliceerd in:Bioessays
Hoofdauteurs: Maciuba, Kevin, Rajasekaran, Nandakumar, Chen, Xiuqi, Kaiser, Christian M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262109/
https://ncbi.nlm.nih.gov/pubmed/33987870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.202100042
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