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Co-translational folding of nascent polypeptides: Multi-layered mechanisms for the efficient biogenesis of functional proteins

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co-translational folding and disti...

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Détails bibliographiques
Publié dans:Bioessays
Auteurs principaux: Maciuba, Kevin, Rajasekaran, Nandakumar, Chen, Xiuqi, Kaiser, Christian M.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262109/
https://ncbi.nlm.nih.gov/pubmed/33987870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.202100042
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