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Co-translational folding of nascent polypeptides: Multi-layered mechanisms for the efficient biogenesis of functional proteins

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co-translational folding and disti...

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Publicat a:Bioessays
Autors principals: Maciuba, Kevin, Rajasekaran, Nandakumar, Chen, Xiuqi, Kaiser, Christian M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262109/
https://ncbi.nlm.nih.gov/pubmed/33987870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.202100042
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