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Co-translational folding of nascent polypeptides: Multi-layered mechanisms for the efficient biogenesis of functional proteins

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co-translational folding and disti...

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Vydáno v:Bioessays
Hlavní autoři: Maciuba, Kevin, Rajasekaran, Nandakumar, Chen, Xiuqi, Kaiser, Christian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262109/
https://ncbi.nlm.nih.gov/pubmed/33987870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.202100042
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