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Apoptosis Induction byHistone Deacetylase Inhibitors in Cancer Cells: Role of Ku70

Histone deacetylases (HDACs) are a group of enzymes that regulate gene transcription by controlling deacetylation of histones and non-histone proteins. Overexpression of HDACs is found in some types of tumors and predicts poor prognosis. Five HDAC inhibitors are approved for the treatment of cutaneo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gong, Ping, Wang, Yuetong, Jing, Yongkui
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480544/
https://ncbi.nlm.nih.gov/pubmed/30935057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071601
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