A Cetuximab-Mediated Suicide System in Chimeric Antigen Receptor–Modified Hematopoietic Stem Cells for Cancer Therapy

Using gene modification of hematopoietic stem cells (HSC) to create persistent generation of multilineage immune effectors to target cancer cells directly is proposed. Gene-modified human HSC have been used to introduce genes to correct, prevent, or treat diseases. Concerns regarding malignant trans...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Kao, Roy L., Truscott, Laurel C., Chiou, Tzu-Ting, Tsai, Wenting, Wu, Anna M., De Oliveira, Satiro N.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479239/
https://ncbi.nlm.nih.gov/pubmed/30860401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.180
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