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In Vitro Generation of Human NK cells Expressing Chimeric Antigen Receptor through Differentiation of Gene-Modified Hematopoietic Stem Cells

NK cells represent a very promising source for adoptive cellular approaches for cancer immunotherapy, and extensive research has been conducted, including clinical trials. Gene modification of NK cells can direct their specificity and enhance their function, but the efficiency of gene transfer techn...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Lowe, Emily, Truscott, Laurel C., De Oliveira, Satiro N.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065352/
https://ncbi.nlm.nih.gov/pubmed/27177671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3684-7_20
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