Pre-clinical development of gene modification of haematopoietic stem cells with chimeric antigen receptors for cancer immunotherapy

Patients with refractory or recurrent B-lineage hematologic malignancies have less than 50% of chance of cure despite intensive therapy and innovative approaches are needed. We hypothesize that gene modification of haematopoietic stem cells (HSC) with an anti-CD19 chimeric antigen receptor (CAR) wil...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Larson, Sarah M., Truscott, Laurel C., Chiou, Tzu-Ting, Patel, Amie, Kao, Roy, Tu, Andy, Tyagi, Tulika, Lu, Xiang, Elashoff, David, De Oliveira, Satiro N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443385/
https://ncbi.nlm.nih.gov/pubmed/28059624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1268745
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados