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A survival selection strategy for engineering synthetic binding proteins that specifically recognize post-translationally phosphorylated proteins
There is an urgent need for affinity reagents that target phospho-modified sites on individual proteins; however, generating such reagents remains a significant challenge. Here, we describe a genetic selection strategy for routine laboratory isolation of phospho-specific designed ankyrin repeat prot...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478843/ https://ncbi.nlm.nih.gov/pubmed/31015433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09854-y |
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