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Twin-arginine translocase mutations that suppress folding quality control and permit export of misfolded substrate proteins
The bacterial twin-arginine translocation (Tat) pathway facilitates the transport of correctly folded proteins across the tightly sealed cytoplasmic membrane. Here, we report the isolation and characterization of suppressor mutations in the Tat translocase that allow export of misfolded proteins, wh...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421223/ https://ncbi.nlm.nih.gov/pubmed/22847444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210140109 |
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