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An inner activation gate controls TMEM16F phospholipid scrambling
Transmembrane protein 16F (TMEM16F) is an enigmatic Ca(2+)-activated phospholipid scramblase (CaPLSase) that passively transports phospholipids down their chemical gradients and mediates blood coagulation, bone development and viral infection. Despite recent advances in the structure and function un...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478717/ https://ncbi.nlm.nih.gov/pubmed/31015464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09778-7 |
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