YAP-independent mechanotransduction drives breast cancer progression

Increased tissue stiffness is a driver of breast cancer progression. The transcriptional regulator YAP is considered a universal mechanotransducer, based largely on 2D culture studies. However, the role of YAP during in vivo breast cancer remains unclear. Here, we find that mechanotransduction occur...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Lee, Joanna Y., Chang, Jessica K., Dominguez, Antonia A., Lee, Hong-pyo, Nam, Sungmin, Chang, Julie, Varma, Sushama, Qi, Lei S., West, Robert B., Chaudhuri, Ovijit
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478686/
https://ncbi.nlm.nih.gov/pubmed/31015465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09755-0
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker