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Identification of cell context-dependent YAP-associated proteins reveals β(1) and β(4) integrin mediate YAP translocation independently of cell spreading
Yes-associated protein (YAP) is a transcriptional regulator and mechanotransducer, relaying extracellular matrix (ECM) stiffness into proliferative gene expression in 2D culture. Previous studies show that YAP activation is dependent on F-actin stress fiber mediated nuclear pore opening, however the...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868278/ https://ncbi.nlm.nih.gov/pubmed/31748579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53659-4 |
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