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TCR affinity biases Th cell differentiation by regulating CD25, Eef1e1, and Gbp2
Naïve CD4(+) T lymphocytes differentiate into various Th cell subsets following TCR binding to microbial peptide:MHCII (p:MHCII) complexes on dendritic cells (DCs). The affinity of the TCR interaction with p:MHCII plays a role in Th differentiation by mechanisms that are not completely understood. W...
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| Опубликовано в: : | J Immunol |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478541/ https://ncbi.nlm.nih.gov/pubmed/30858199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801609 |
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