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Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells

Dormant cancer cells known as disseminated tumor cells (DTCs) are often present in bone marrow of breast cancer patients. These DTCs are thought to be responsible for the incurable recurrence of breast cancer. The mechanism underlying the long-term maintenance of DTCs remains unclear, however. Here,...

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書誌詳細
出版年:JCI Insight
主要な著者: Shimizu, Hideyuki, Takeishi, Shoichiro, Nakatsumi, Hirokazu, Nakayama, Keiichi I.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478422/
https://ncbi.nlm.nih.gov/pubmed/30830867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125138
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