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Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells

Dormant cancer cells known as disseminated tumor cells (DTCs) are often present in bone marrow of breast cancer patients. These DTCs are thought to be responsible for the incurable recurrence of breast cancer. The mechanism underlying the long-term maintenance of DTCs remains unclear, however. Here,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Shimizu, Hideyuki, Takeishi, Shoichiro, Nakatsumi, Hirokazu, Nakayama, Keiichi I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478422/
https://ncbi.nlm.nih.gov/pubmed/30830867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125138
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