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Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells

In addition to the properties of self-renewal and multipotency, stem cells are characterised by their distinct cell cycle status. Somatic stem cells are maintained in a quiescent state but switch reversibly from quiescence to proliferation as needed. On the other hand, embryonic stem cells and induc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Br J Cancer
Hauptverfasser: Takeishi, S, Nakayama, K I
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453837/
https://ncbi.nlm.nih.gov/pubmed/24853181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.259
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