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Small molecule activators of the p53 response

Drugging the p53 pathway has been a goal for both academics and pharmaceutical companies since the designation of p53 as the ‘guardian of the genome’. Through growing understanding of p53 biology, we can see multiple routes for activation of both wild-type p53 function and restoration of mutant p53....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Biol
Egile Nagusiak: Ladds, Marcus J G W, Laín, Sonia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478124/
https://ncbi.nlm.nih.gov/pubmed/30689917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz006
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