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An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells

Pharmacological activation of wild-type p53 has been found to protect normal cells in culture from cytotoxicity and nuclear aberrations caused by conventional cancer therapeutics. Hence, small-molecule p53 activators could have clinical benefits as chemoprotectants for cancer patients bearing p53-mu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: van Leeuwen, Ingeborg M.M., Rao, Bhavya, Sachweh, Marijke C.C., Laín, Sonia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372395/
https://ncbi.nlm.nih.gov/pubmed/22517433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20254
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