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Site-Specific Modification of Single-Chain Antibody Fragments for Bioconjugation and Vascular Immunotargeting

The conjugation of antibodies to drugs and drug carriers improves delivery to target tissues. Widespread implementation and effective translation of this pharmacologic strategy awaits the development of affinity ligands capable of a defined degree of modification and highly efficient bioconjugation...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Greineder, Colin F., Villa, Carlos H., Walsh, Landis R., Kiseleva, Raisa Y., Hood, Elizabeth D., Khoshnejad, Makan, Warden-Rothman, Robert, Tsourkas, Andrew, Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477694/
https://ncbi.nlm.nih.gov/pubmed/29200285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00592
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