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Sortase-Tag Expressed Protein Ligation (STEPL): combining protein purification and site-specific bioconjugation into a single step

Efficient labeling of protein-based targeting ligands with various cargos (drugs, imaging agents, nanoparticles, etc.) is essential to the fields of molecular imaging and targeted therapeutics. Many common bioconjugation techniques, however, are inefficient, non-stoichiometric, not site-specific, an...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Warden-Rothman, Robert, Caturegli, Ilaria, Popik, Vladimir, Tsourkas, Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843242/
https://ncbi.nlm.nih.gov/pubmed/24111659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402871k
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