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Utilizing Selenocysteine for Expressed Protein Ligation and Bioconjugations

Employing selenocysteine-containing protein fragments to form the amide bond between respective protein fragments significantly extends current capabilities of the widely used protein engineering method, expressed protein ligation. Selenocysteine-mediated ligation is noteworthy for its high yield an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Liu, Jun, Chen, Qingqing, Rozovsky, Sharon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824972/
https://ncbi.nlm.nih.gov/pubmed/28186733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10991
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