Improved Hematopoiesis in GS-Nitroxide (JP4-039)-treated Mouse Long-term Bone Marrow Cultures and Radioresistance of Derived Bone Marrow Stromal Cell Lines

AIM: To determine if the small-molecule radioprotector GS-nitroxide, JP4-039, improved hematopoiesis in long-term bone marrow cultures (LTBMCs), explanted marrow from in vivo drug-treated C57BL/6NTac mice was maintained in JP4-039 for 25 weeks. Hematopoietic cell production and radiobiology of deriv...

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Publicado no:In Vivo
Main Authors: SHINDE, ASHWIN, EPPERLY, MICHAEL W., CAO, SHAONAN, HOLT, DOUGLAS, GOFF, JULIE, SHIELDS, DONNA, FRANICOLA, DARCY, WIPF, PETER, WANG, HONG, GREENBERGER, JOEL S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477534/
https://ncbi.nlm.nih.gov/pubmed/25189880
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