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EPEN-06. YAP1 SUBGROUP SUPRATENTORIAL EPENDYMOMA REQUIRES TEAD AND NUCLEAR FACTOR I-MEDIATED TRANSCRIPTIONAL PROGRAMS FOR TUMORIGENESIS

Ependymoma (EPN) is one of the most aggressive pediatric brain tumors, often arising in the supratentorial (ST) region. Our previous DNA methylation profiling study has identified ST-EPN subgroups that are characterized by YAP1-related fusions through genomic structural rearrangements (hereafter cal...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Pajtler, Kristian, Wei, Yiju, Okonechniov, Konstantin, Vouri, Mikaella, Sahm, Felix, Bunt, Jens, Jones, David, Korshunov, Andrey, Lichter, Peter, Pfister, Stefan, Kool, Marcel, Li, Wei, Kawauchi, Daisuke
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.063
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