EPEN-03. ZFTA/C11ORF95 FUSIONS DRIVE SUPRATENTORIAL EPENDYMOMA VIA SHARED ONCOGENIC MECHANISMS

The majority of supratentorial ependymomas (ST-EPN) are driven by fusion genes between RELA and zinc finger translocation associated, ZFTA, previously named C11orf95. Apart from fusions with a portion of the Hippo effector YAP1, which affects a small group of infant patients, the oncogenic mechanism...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Zheng, Tuyu, Ghasemi, David R, Okonechnikov, Konstantin, Korshunov, Andrey, Maaß, Kendra K, Sill, Martin, Gojo, Johannes, Schüller, Ulrich, Milde, Till, Mack, Stephen C, Gilbertson, Richard J, von Deimling, Andreas, Jones, David T W, Kool, Marcel, Pfister, Stefan M, Sahm, Felix, Kawauchi, Daisuke, Pajtler, Kristian W
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Ependymoma
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168100/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.053
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