HGG-25. TARGETING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND HIGH GRADE GLIOMAS INHIBITS PROLIFERATION, INVASION AND TUMORIGENICITY

Diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM) are infiltrative and lethal brain tumors. Identifying and targeting novel molecular markers is urgently needed. Although DIPG and GBM have different epigenetic drivers, we found increased expression of an epigenetic modifier and stem cel...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Kaur, Harpreet, Guo, Huizi, Akhtarkhavari, Sepehr, Eberhart, Charles, Raabe, Eric
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
High Grade Glioma
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477394/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.119
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