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HGG-25. TARGETING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND HIGH GRADE GLIOMAS INHIBITS PROLIFERATION, INVASION AND TUMORIGENICITY

Diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM) are infiltrative and lethal brain tumors. Identifying and targeting novel molecular markers is urgently needed. Although DIPG and GBM have different epigenetic drivers, we found increased expression of an epigenetic modifier and stem cel...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kaur, Harpreet, Guo, Huizi, Akhtarkhavari, Sepehr, Eberhart, Charles, Raabe, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477394/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.119
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