Φορτώνει......
MEDU-06. TARGETING MYC AND OTX2-DRIVEN TRANSCRIPTIONAL DEPENDENCIES OF GROUP 3 MEDULLOBLASTOMA THROUGH CDK7 INHIBITION
Medulloblastoma (MB) is the most frequent malignant childhood brain cancer and Group 3 MB (G3-MB) has the worst prognosis among the four consensus molecular subtypes. In G3-MB, MYC and OTX2 have been shown to be the oncogenic drivers and master transcriptional factors that tumor cells are highly add...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neuro Oncol |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477377/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.166 |
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