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IMMU-06. INVESTIGATING IMMUNOSUPPRESSIVE MECHANISMS IN THE TUMOR MICROENVIRONMENT OF HIGH-RISK NEUROBLASTOMA; AN IMMUNOCOMPETENT, MYCN-DRIVEN, NON-GERMLINE GEM MODEL
Combining anti-GD2 ganglioside monoclonal antibody with immune-activating cytokines improves survival in high-risk neuroblastoma, a breakthrough for immunotherapy in this disease. However, approaches such as immune checkpoint blockade, anti-GD2 CAR-T cells, and tumor vaccines have thus far shown lim...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477359/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.127 |
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