MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma

A wide range of malignancies presents MYCN amplification (MNA) or dysregulation. MYCN is associated with poor prognosis and its over-expression leads to several dysregulations including metabolic reprogramming, mitochondria alteration, and cancer stem cell phenotype. Some hints suggest that MYCN ove...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Raieli, Salvatore, Di Renzo, Daniele, Lampis, Silvia, Amadesi, Camilla, Montemurro, Luca, Pession, Andrea, Hrelia, Patrizia, Fischer, Matthias, Tonelli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951059/
https://ncbi.nlm.nih.gov/pubmed/33718189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.625207
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