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MYCN Function in Neuroblastoma Development

Dysregulated expression of the transcription factor MYCN is frequently detected in nervous system tumors such as childhood neuroblastoma. Here, gene amplification of MYCN is a single oncogenic driver inducing neoplastic transformation in neural crest-derived cells. This abnormal MYCN expression is o...

詳細記述

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書誌詳細
出版年:Front Oncol
主要な著者: Otte, Jörg, Dyberg, Cecilia, Pepich, Adena, Johnsen, John Inge
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873735/
https://ncbi.nlm.nih.gov/pubmed/33585251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.624079
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