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MYCN Function in Neuroblastoma Development
Dysregulated expression of the transcription factor MYCN is frequently detected in nervous system tumors such as childhood neuroblastoma. Here, gene amplification of MYCN is a single oncogenic driver inducing neoplastic transformation in neural crest-derived cells. This abnormal MYCN expression is o...
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| Publicado no: | Front Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873735/ https://ncbi.nlm.nih.gov/pubmed/33585251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.624079 |
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