ATRT-10. HETEROGENEITY OF BAF AND PBAF SWI/SNF COMPLEX SUBUNITS IN MALIGNANT RHABDOID TUMORS RELATES WITH POLYPHENOTYPIC DIFFERENTIATION AND THE IMMUNE MICROENVIRONMENT

Malignant Rhabdoid Tumors (MRT’s) are aggressive tumors characterized by loss of the SWI/SNF complex protein SMARCB1. They occur in the CNS (atypical teratoid/rhabdoid tumors-AT/RT) or outside (extra-CNS, eCNS). MRTs are defined by tumor cells that exhibit varying cell lineage phenotypes including n...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Venneti, Sriram, Panwalkar, Pooja, Pratt, Drew, Chung, Chan, Martinez, Daniel, Dang, Derek, Bayliss, Jill, Le, Paul, Margol, Ashley, Pawel, Bruce, Judkins, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Atypical Teratoid Rhabdoid Tumor (ATRT)
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477331/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.009
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