ATRT-22. SWI/SNF COMPLEX HETEROGENEITY RELATES WITH POLYPHENOTYPIC DIFFERENTIATION AND THE IMMUNE MICRO ENVIRONMENT IN RHABDOID TUMORS

Malignant rhabdoid tumors (MRT), including central nervous system (CNS) Atypical Teratoid / Rhabdoid Tumors (AT/RT) and extra CNS (eCNS) MRT, are aggressive cancers characterized by loss of SMARCB1, a core component of the SWI/SNF chromatin-remodeling complex. Histopathologically, MRTs are character...

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Publicado no:Neuro Oncol
Main Authors: Venneti, Sriram, Panwalkar, Pooja, Chung, Chan, Pratt, Drew, Martinez, Daniel, Bayliss, Jill, Paran, Christopher, Hawes, Debra, Pawel, Bruce, Judkins, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011973/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.020
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